Current Osteoarthritis (OA) Studies
Below is a summary of our current Osteoarthritis trials. If you are interested in learning more, simply click on the trial's name to answer a few qualifying questions and request a contact by our research staff:
Tanezumab OA of the Hip or Knee Study:
Tanezumab is a drug being studied to see how effective it is at relieving osteoarthritis pain. Tanezumab will be compared to non-steroidal anti-inflammatory drugs (NSAIDS) on long-term joint safety and pain relief. The NSAIDs used for comparison in this study are naproxen, celecoxib or diclofenac. Tanezumab is given by subcutaneous injection just under the skin every 8 weeks. The study lasts about 21 months and there are at least 15 visits during that time. All study procedures including blood tests, x-rays, MRI, and study-related care by an arthritis specialist are provided at no charge. Reimbursement may be provided for time and travel expenses.
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What is Osteoarthritis?
Osteoarthritis (OA) is a common type of arthritis in which there is a gradual loss of cartilage from the joints. Common osteoarthritis symptoms include pain, stiffness, some loss of joint motion, and changes in the shape of affected joints. Although OA can affect almost any joint, it most often affects the hands, knees, hips, and spine. Osteoarthritis is a chronic condition that gradually worsens over time; however, there are several measures that may slow its progression and control symptoms. The diagnosis of OA is the first step in ensuring the appropriate treatment of osteoarthritis.
Osteoarthritis Risk Factors:
- Age - This is a chronic condition that gradually worsens over time; symptoms are rare in those below the age of 40 but are present, at least in x-ray by 80% of people 55 years or older. However x-ray appearance does not translate into symptoms of pain in all people.
- Gender - Although the reason is unknown, women are 2-3 times more likely to develop OA than men.
- Obesity - Excessive weight increases the risk of osteoarthritis. Weight loss can decrease this link.
- Occupation - Certain occupations that require excessive squatting, kneeling, lifting heavy objects, standing and walking are linked to higher incidences of OA.
- OA has been found in individuals that participated in certain sports such as wrestling, football, gymnastics, soccer, parachuting, boxing, cycling, and ballet dancing. Surprisingly, running has not been linked to an increase in OA.